Idiopathic pulmonary arterial hypertension patients with a high H2FPEF-score: Insights from the Amsterdam UMC PAH-cohort
Azar Kianzad, Jessie van Wezenbeek, Lucas R. Celant, Frank Oosterveer, Anton Vonk Noordegraaf, Lilian J. Meijboom, Frances S. de Man, Harm Jan Bogaard, M. Louis Handoko
Abstract
BACKGROUND: The idiopathic pulmonary arterial hypertension (iPAH) phenotype is changing from a predominantly young female patient to an older, frequently obese patient of either sex. Many newly diagnosed iPAH-patients have risk factors for left ventricular diastolic dysfunction (LVDD), possibly affecting management and treatment. AIM: FPEF-score identifies a subgroup of iPAH-patients with blunted response to PAH-targeted treatment. STUDY DESIGN AND METHODS: FPEF-score; a score ≥5 identified a higher possibility of (concealed) LVDD. RESULTS: FPEF-score. CONCLUSIONS: FPEF-score.