Litcius/Paper detail

Saikosaponin A triggers cell ferroptosis in hepatocellular carcinoma by inducing endoplasmic reticulum stress-stimulated ATF3 expression

Tian Lan, Wen Wang, Xi-xi Zeng, Yuhua Tong, Zhu-Jun Mao, Siwei Wang, Siwei Wang

2023Biochemical and Biophysical Research Communications41 citationsDOI

Topics & Concepts

GlutathioneEndoplasmic reticulumUnfolded protein responseProgrammed cell deathGPX4IntracellularCell biologyDownregulation and upregulationLipid peroxidationChemistryBiologyOxidative stressCancer researchMolecular biologyBiochemistryApoptosisEnzymeGlutathione peroxidaseGeneFerroptosis and cancer prognosisCancer-related molecular mechanisms researchCancer, Lipids, and Metabolism