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CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors

B. Thirupataiah, Guntipally Mounika, Gangireddy Sujeevan Reddy, J.S. Dileep Kumar, Ravikumar Kapavarapu, Raghavender Medishetti, Jayesh Mudgal, Jessy Elizabeth Mathew, Gautham G. Shenoy, C. Mallikarjuna Rao, Kiranam Chatti, Kishore V. L. Parsa, Manojit Pal

2021Bioorganic Chemistry16 citationsDOI

Topics & Concepts

ChemistryMoietyCombinatorial chemistryLigand (biochemistry)Yield (engineering)CatalysisStereochemistryOrganic chemistryBiochemistryReceptorMaterials scienceMetallurgySynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and ActivitiesSulfur-Based Synthesis Techniques
CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling–cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors | Litcius