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Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome

Subhendu Das, Sharmistha Karmakar, Harish Venkatachalapathy, Rajeev Jha, Eric Batchelor, David Levens

2024Molecular Cell17 citationsDOIOpen Access PDF

Topics & Concepts

BiologyDNA damageCancer researchDegradation (telecommunications)DNACell biologyGeneticsComputer scienceTelecommunicationsCancer therapeutics and mechanismsDNA Repair MechanismsCancer-related Molecular Pathways
Excessive MYC-topoisome activity triggers acute DNA damage, MYC degradation, and replacement by a p53-topoisome | Litcius