Synthesis, cytotoxicity, and in vivo antitumor activity study of parthenolide semicarbazones and thiosemicarbazones
Xinxin Jia, Qi Liu, Shi‐Yi Wang, Binglin Zeng, Guohua Du, Chen Zhang, Yan Li
Topics & Concepts
ParthenolideChemistryCytotoxicitySesquiterpene lactoneIn vivoSemicarbazoneIn vitroSesquiterpeneCell cultureStructure–activity relationshipApoptosisStereochemistryBiological activityPharmacologyBiochemistryBiotechnologyBiologyGeneticsMedicineSesquiterpenes and Asteraceae StudiesNatural product bioactivities and synthesisPlant biochemistry and biosynthesis