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Blockade of HIF-1α and STAT3 by hyaluronate-conjugated TAT-chitosan-SPION nanoparticles loaded with siRNA molecules prevents tumor growth

Hendrik Setia Budi, Sepideh Izadi, Anton Timoshin, Sima Heydarzadeh Asl, Behzad Beyzai, Amir Ghaderpour, Fatemeh Alian, Farzaneh Sadat Eshaghi, Seyedeh Mahboubeh Mousavi, Behnam Rafiee, Afshin Nikkhoo, Armin Ahmadi, Hadi Hassannia, Majid Ahmadi, Mozhdeh Sojoodi, Farhad Jadidi‐Niaragh

2021Nanomedicine Nanotechnology Biology and Medicine34 citationsDOI

Topics & Concepts

In vivoCancer cellCancer researchChemistryGene silencingSTAT3ApoptosisDownregulation and upregulationTransfectionImmune systemCancerImmunologyBiologyMedicineBiochemistryInternal medicineBiotechnologyGeneCancer, Hypoxia, and MetabolismMicroRNA in disease regulationChemokine receptors and signaling
Blockade of HIF-1α and STAT3 by hyaluronate-conjugated TAT-chitosan-SPION nanoparticles loaded with siRNA molecules prevents tumor growth | Litcius