Lentivirally administered glial cell line-derived neurotrophic factor promotes post-ischemic neurological recovery, brain remodeling and contralesional pyramidal tract plasticity by regulating axonal growth inhibitors and guidance proteins
Merve Beker, Ahmet B. Çağlayan, Mustafa Çağlar Beker, Serdar Altunay, Reyda Karaçay, Arman Dalay, Mehmet Özgen Altıntaş, Gamze Torun Köse, Dirk M. Hermann, Ertuğrul Kılıç
Topics & Concepts
Glial cell line-derived neurotrophic factorNeuroscienceNeurotrophic factorsNeurogenesisNeuroprotectionNeuroplasticityGlial scarNeurotrophinCorticospinal tractMedicineBiologyCentral nervous systemInternal medicineReceptorAstrocyteDiffusion MRIRadiologyMagnetic resonance imagingAxon Guidance and Neuronal SignalingNerve injury and regenerationNeurogenesis and neuroplasticity mechanisms