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Vaccines and Disease Relapses in Children with Nephrotic Syndrome

Andrea Angeletti, Maurizio Bruschi, Silvia Bianchin, Irene Bonato, Carolina Montobbio, Enrico Verrina, Francesca Lugani, Paolo Cravedi, Gian Marco Ghiggeri

2021Clinical Journal of the American Society of Nephrology24 citationsDOIOpen Access PDF

Abstract

More than half of children with idiopathic nephrotic syndrome develop frequent relapses or steroid dependence and require chronic use of immune suppressants, such as cyclosporin, mycophenolate mofetil, or B cell–depleting therapies, to maintain disease in remission ([1][1]). Loss of endogenous

Topics & Concepts

MedicineNephrotic syndromeMycophenolateDiseaseMinimal change diseaseIdiopathic Nephrotic SyndromePediatricsImmunologyImmune systemGlomerulonephritisInternal medicineTransplantationProteinuriaFocal segmental glomerulosclerosisKidneyRenal Diseases and GlomerulopathiesAutoimmune Bullous Skin DiseasesImmunodeficiency and Autoimmune Disorders