Au/Ag synergistic catalysis of synthesis of 4 <i>H</i> -imidazo-oxadiazin-4-ones <i>via</i> three-component domino cyclization
Dongfang Jiang, Feng Liu, Can Yang, Xin Li, Hongchi Zhou, Haifei Wang, Zhenjie Qi
Abstract
A novel and efficient method for synthesizing a wide range of 4 H -imidazo-oxadiazin-4-ones was achieved through a three-component domino cyclization reaction of N -tosylhydrazones with α,β-unsaturated acids and amines.
Topics & Concepts
ChemistryDominoCascadeCatalysisCascade reactionComponent (thermodynamics)Combinatorial chemistryMedicinal chemistryOrganic chemistryChromatographyThermodynamicsPhysicsSynthesis and Biological EvaluationCyclopropane Reaction MechanismsCatalytic C–H Functionalization Methods