Trypanosoma cruzi Isolates Naturally Adapted to Congenital Transmission Display a Unique Strategy of Transplacental Passage
Paula Faral‐Tello, Gonzalo Greif, Selva Romero, Andrés Cabrera, Cristina Oviedo, Telma González, Gabriela Libisch, Ana Paula Arévalo, Belén Varela, José Manuel Verdes, Martina Crispo, Yester Basmadjián, Carlos Robello
Abstract
The main findings of this study are that we determined that there are Trypanosoma cruzi strains adapted to transplacental transmission and completely different from the commonly used laboratory reference strains. This implies a specific strategy for the vertical transmission of Chagas disease.
Topics & Concepts
VirulenceBiologyTrypanosoma cruziParasitemiaChagas diseaseTransmission (telecommunications)Horizontal transmissionVirologyTransplacentalMicrobiologyImmune systemPlacentaGeneImmunologyGeneticsParasite hostingFetusPregnancyVirusComputer scienceElectrical engineeringMalariaPlasmodium falciparumWorld Wide WebEngineeringTrypanosoma species research and implicationsResearch on Leishmaniasis StudiesInsect symbiosis and bacterial influences