Immune Checkpoint VISTA Negatively Regulates Microglia Glycolysis and Activation via TRIM28-Mediated Ubiquitination of HK2 in Sepsis-Associated Encephalopathy
Yuhai Xu, Ying Zhu, Yue Shi, Bo Ye, Lulong Bo, Tianzhu Tao
Topics & Concepts
MicrogliaUbiquitinSepsisImmune systemEncephalopathyImmune checkpointGlycolysisCancer researchImmunologyInflammationMedicineNeuroscienceCell biologyBiologyGeneticsImmunotherapyPsychiatryInternal medicineGeneMetabolismNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerImmune Response and Inflammation