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Design, synthesis and biological evaluation of novel benzofuran derivatives as potent LSD1 inhibitors

Xiangyu Zhang, Hai‐Lan Huang, Ziheng Zhang, Jiangkun Yan, Tianxiao Wu, Wenbo Yin, Yixiang Sun, Xinran Wang, Yanting Gu, Dongmei Zhao, Maosheng Cheng

2021European Journal of Medicinal Chemistry36 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryBenzofuranChemical synthesisCombinatorial chemistryBiological activityStereochemistryBiochemistryIn vitroEpigenetics and DNA MethylationChemical Reactions and IsotopesNeuroendocrine regulation and behavior
Design, synthesis and biological evaluation of novel benzofuran derivatives as potent LSD1 inhibitors | Litcius