Mast Cells and Interleukins
Antonio Giovanni Solimando, Vanessa Desantis, Doménico Ribatti
Abstract
Mast cells play a critical role in inflammatory diseases and tumor growth. The versatility of mast cells is reflected in their ability to secrete a wide range of biologically active cytokines, including interleukins, chemokines, lipid mediators, proteases, and biogenic amines. The aim of this review article is to analyze the complex involvement of mast cells in the secretion of interleukins and the role of interleukins in the regulation of biological activities of mast cells.
Topics & Concepts
Interleukin 33Mast cellSecretionProteasesChemokineInterleukinMast (botany)ImmunologyBiologyCell biologyInflammationCytokineBiochemistryEnzymeMast cells and histamineAsthma and respiratory diseasesUrticaria and Related Conditions