Eco-friendly stability-indicating HPTLC micro-determination of the first FDA approved SARS-CoV-2 antiviral prodrug Remdesivir: Study of degradation kinetics and structural elucidation of the degradants using HPTLC-MS
Amira H. Abo-Gharam, Dina S. El‐Kafrawy
Topics & Concepts
ChromatographyChemistryProdrugCoronavirus disease 2019 (COVID-19)Alkaline hydrolysisSilica gelHydrolysisDegradation (telecommunications)Organic chemistryMedicineBiochemistryInfectious disease (medical specialty)TelecommunicationsDiseaseComputer sciencePathologyAnalytical Methods in PharmaceuticalsAnalytical Chemistry and ChromatographyAntibiotics Pharmacokinetics and Efficacy