The miR-103a-3p/TGFBR3 axis regulates TGF-β-induced orbital fibroblast activation and fibrosis in thyroid-eye disease
Bingyu Xie, Wei Xiong, Feng Zhang, Nuo Wang, Yong Luo, Yizhi Chen, Jiamin Cao, Zhuo-Kun Chen, Chen Ma, Haiyan Chen
Topics & Concepts
FibroblastVimentinSMADDownregulation and upregulationSignal transductionTransforming growth factorFibronectinCancer researchEpithelial–mesenchymal transitionMAPK/ERK pathwayBiologyEndocrinologyChemistryInternal medicineCell biologyCell cultureMedicineImmunologyExtracellular matrixImmunohistochemistryGeneBiochemistryGeneticsOphthalmology and Eye DisordersCerebral Venous Sinus ThrombosisGlaucoma and retinal disorders