Litcius/Paper detail

In vivo cytidine base editing of hepatocytes without detectable off-target mutations in RNA and DNA

Lukas Villiger, Tanja Rothgangl, Dominik Witzigmann, Rurika Oka, Paulo J.C. Lin, Weihong Qi, Sharan Janjuha, Christian Berk, Femke Ringnalda, Mitchell Beattie, Markus Stoffel, Beat Thöny, Jonathan Hall, Hubert Rehrauer, Ruben van Boxtel, Ying K. Tam, Gerald Schwank

2021Nature Biomedical Engineering102 citationsDOIOpen Access PDF

Topics & Concepts

CytidineRNARNA editingBiologyCytidine deaminaseTranscriptomeDNAGenome editingMolecular biologyBase pairGeneticsComputational biologyGenomeGeneGene expressionBiochemistryEnzymeCRISPR and Genetic EngineeringRNA regulation and diseaseRNA and protein synthesis mechanisms