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Structural insights into the assembly and substrate selectivity of human SPT–ORMDL3 complex

Sisi Li, Tian Xie, Peng Liu, Lei Wang, Xin Gong

2021Nature Structural & Molecular Biology96 citationsDOI

Topics & Concepts

SphingolipidSerineSubstrate (aquarium)BiologySelectivityBiochemistryStereochemistryBiosynthesisHydrolaseDimerCell biologyEnzymeChemistryCatalysisOrganic chemistryEcologySphingolipid Metabolism and SignalingEndoplasmic Reticulum Stress and DiseaseLysosomal Storage Disorders Research
Structural insights into the assembly and substrate selectivity of human SPT–ORMDL3 complex | Litcius