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Disentangling the signaling pathways of mTOR complexes, mTORC1 and mTORC2, as a therapeutic target in glioblastoma

Meena Jhanwar‐Uniyal, Jose F. Dominguez, Avinash Mohan, Michael Tobias, Chirag D. Gandhi

2021Advances in Biological Regulation22 citationsDOI

Topics & Concepts

mTORC2mTORC1PI3K/AKT/mTOR pathwayRHEBCell biologyMechanistic target of rapamycinPTENPhosphorylationRPTORCancer researchBiologyProtein kinase BCell growthSignal transductionChemistryBiochemistryPI3K/AKT/mTOR signaling in cancerMelanoma and MAPK PathwaysCancer Mechanisms and Therapy
Disentangling the signaling pathways of mTOR complexes, mTORC1 and mTORC2, as a therapeutic target in glioblastoma | Litcius