High-content stimulated Raman histology of human breast cancer
Hongli Ni, Chinmayee Vallabh Prabhu Dessai, Haonan Lin, Wei Wang, Shaoxiong Chen, Yuhao Yuan, Xiaowei Ge, Jianpeng Ao, Nolan Vild, Ji‐Xin Cheng
Abstract
: HC-SRH provides both morphological and chemical information of tissue in a label-free manner. The chemical information detected is beyond the reach of traditional hematoxylin and eosin staining and heralds the potential of HC-SRH for biomarker discovery.
Topics & Concepts
HistologyRaman spectroscopyBiomedical engineeringMaterials scienceExtracellular matrixBreast cancerH&E stainPathologyChemical imagingCancerChemistryStainingMedicineHyperspectral imagingComputer scienceOpticsInternal medicineBiochemistryArtificial intelligencePhysicsSpectroscopy Techniques in Biomedical and Chemical ResearchSpectroscopy and Chemometric AnalysesMolecular Biology Techniques and Applications