Isolation of phytochemical constituents from Stevia rebaudiana (Bert.) and evaluation of their anticancer, antimicrobial and antioxidant properties via in vitro and in silico approaches
Most. Chand Sultana Khatun, Md. Abdul Muhit, Md. Jamal Hossain, Muhammad Abdullah Al-Mansur, Shibley Rahman
Abstract
bioactivities were also supported by molecular docking studies. The computational study demonstrated that the isolated compounds exerted stronger affinity compared to the standard drugs towards the binding sites of dihydrofolate reductase (DHFR), glutathione reductase, and urase oxidase.
Topics & Concepts
DPPHChemistryApigeninPhytochemicalAntimicrobialAntioxidantLuteolinIn silicoIn vitroPharmacophoreBiochemistryQuercetinFlavonoidOrganic chemistryGeneBiochemical Analysis and Sensing TechniquesPhytochemicals and Antioxidant ActivitiesZiziphus Jujuba Studies and Applications