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Base editors for simultaneous introduction of C-to-T and A-to-G mutations

Rina C. Sakata, Soh Ishiguro, Hideto Mori, Mamoru Tanaka, Kenji Tatsuno, Hiroki Ueda, Shogo Yamamoto, M. Seki, Nanami Masuyama, Keiji Nishida, Hiroshi Nishimasu, Kazuharu Arakawa, Akihiko Kondo, Osamu Nureki, Masaru Tomita, Hiroyuki Aburatani, Nozomu Yachie

2020Nature Biotechnology202 citationsDOI

Topics & Concepts

CytosineAdenosine deaminaseCytosine deaminaseBase (topology)Genome editingCas9DNABiologyComputational biologyFunction (biology)AdenosineCRISPRGeneticsBiochemistryGeneGenetic enhancementMathematicsMathematical analysisCRISPR and Genetic EngineeringRNA regulation and diseaseRNA and protein synthesis mechanisms
Base editors for simultaneous introduction of C-to-T and A-to-G mutations | Litcius