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Development and validation of peripheral blood DNA methylation signatures to predict response to biological therapy in adults with Crohn's disease (EPIC-CD): an epigenome-wide association study

V Joustra, Andrew Y. F. Li Yim, Peter Henneman, Ishtu Hageman, Tristan de Waard, Evgeni Levin, Alexandra Noble, Thomas Chapman, Femke Mol, Sarah van Zon, D.Y. Lee, Colleen GC McGregor, Melanie S. Hulshoff, Jack Satsangi, Wouter J. de Jonge, Geert D’Haens, Hans Paulich, Inge van Welsen, Rishand K. Ramkisoen, Yara E. Abeling, Marloes Zwart, Nicole E.M. Berkers, Caroline Verseijden, Anje A. te Velde, Nicola Radcliffe, Aisling Quinn, Beatriz Camesella Perez, Tom Thomas, Rahul Ravindran, James Chivenga, Simon Travis

2025˜The œLancet. Gastroenterology & hepatology14 citationsDOIOpen Access PDF

Topics & Concepts

EpigenomePeripheral bloodEPICDiseaseCrohn's diseaseDNA methylationMedicinePeripheralOncologyImmunologyBioinformaticsInternal medicineBiologyGeneticsGeneLiteratureArtGene expressionInflammatory Bowel DiseaseAutoimmune and Inflammatory DisordersGut microbiota and health
Development and validation of peripheral blood DNA methylation signatures to predict response to biological therapy in adults with Crohn's disease (EPIC-CD): an epigenome-wide association study | Litcius