Dispatched uses Na+ flux to power release of lipid-modified Hedgehog
Qianqian Wang, Daniel Asarnow, Ke Ding, Randall K. Mann, Jason Hatakeyama, Yunxiao Zhang, Yong Ma, Yifan Cheng, Philip A. Beachy
Topics & Concepts
Transmembrane domainTransmembrane proteinHedgehogChemistryHedgehog signaling pathwayFlux (metallurgy)BiophysicsPatchedBiologyBiochemistryAmino acidSignal transductionReceptorOrganic chemistryHedgehog Signaling Pathway StudiesGenomics and Chromatin DynamicsGenetics and Neurodevelopmental Disorders