Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis
Jukka Rantanen, Thomas Rades, Clare J. Strachan
Abstract
The solid state of matter is the preferred starting point for designing a pharmaceutical product. This is driven by both patient preferences and the relative ease of supplying a solid pharmaceutical product with desired quality and performance. Solid form diversity is increasingly prevalent as a crucial element in designing these products, which underpins the importance of solid-state analytical methods. This paper provides a critical analysis of challenges related to solid-state analytics, as well as considerations and suggestions for feasible and meaningful pharmaceutical analysis.
Topics & Concepts
ChemistryBiochemical engineeringSolid-stateAnalyticsProduct (mathematics)Risk analysis (engineering)Management scienceData scienceComputer scienceBusinessEngineeringPhysical chemistryGeometryMathematicsDrug Solubulity and Delivery SystemsInhalation and Respiratory Drug DeliveryAnalytical Chemistry and Chromatography