Antibacterial and safe chitosan–graphene hydrogel films: a promising nanotherapeutic for <i>Staphylococcus aureus</i> wound infections
Priyadarshani Choudhary, Baskaran Ramalingam, Somashree Bose, Sujoy K. Das
Abstract
studies on Wistar rat model demonstrated superior bacterial eradication and wound healing compared to antibiotic treatment. The CGrAP hydrogel also showed excellent physicochemical properties, including porosity, water uptake and cytocompatibility with L929 fibroblast cells along with no skin irritation or acute dermal toxicity. These results suggest that, CGrAP nanocomposite hydrogel films have strong potential for antibacterial wound dressing development in chronic wound care.
Topics & Concepts
Staphylococcus aureusChitosanChemistryMicrobiologyWound infectionGrapheneSelf-healing hydrogelsWound healingNanotechnologyBacteriaMaterials scienceBiologyMedicineImmunologyBiochemistryPolymer chemistrySurgeryGeneticsGraphene and Nanomaterials ApplicationsNanoparticles: synthesis and applicationsBone Tissue Engineering Materials