A fluorescent ESIPT-based benzimidazole platform for the ratiometric two-photon imaging of ONOO<sup>−</sup><i>in vitro</i> and <i>ex vivo</i>
Maria L. Odyniec, Sang-Jun Park, Jordan E. Gardiner, Emily C. Webb, Adam C. Sedgwick, Juyoung Yoon, Steven D. Bull, Hwan Myung Kim, Tony D. James
Abstract
in RAW264.7 macrophages and rat hippocampus tissue. These results demonstrate the utility of this ESIPT benzimidazole-based platform for theranostic development and bioimaging applications.
Topics & Concepts
BenzimidazoleEx vivoFluorescenceChemistryTwo-photon excitation microscopyIn vivoBiophysicsIn vitroFluorescence-lifetime imaging microscopyPhotochemistryBiochemistryOrganic chemistryOpticsPhysicsBiologyBiotechnologyMolecular Sensors and Ion DetectionNanoplatforms for cancer theranosticsAnalytical Chemistry and Sensors