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Akt phosphorylation regulated by IKKε in response to low shear stress leads to endothelial inflammation via activating IRF3

Linlin Zhu, Hongfeng Yang, Yuelin Chao, Yue Gu, Junxia Zhang, Feng Wang, Wande Yu, Peng Ye, Peng Chu, Xiangquan Kong, Shao‐Liang Chen

2020Cellular Signalling17 citationsDOI

Topics & Concepts

Protein kinase BPhosphorylationPI3K/AKT/mTOR pathwayIκB kinaseCell biologyCancer researchGene silencingIRF3InflammationChemistrySignal transductionBiologyNF-κBImmunologyBiochemistryTranscription factorGeneinterferon and immune responsesCancer-related molecular mechanisms researchCytokine Signaling Pathways and Interactions
Akt phosphorylation regulated by IKKε in response to low shear stress leads to endothelial inflammation via activating IRF3 | Litcius