Dietary methionine supplementation during the estrous cycle improves follicular development and estrogen synthesis in rats
Guangxin Yang, Siyu Li, Shuang Cai, Junyan Zhou, Qianhong Ye, Shihai Zhang, Fang Chen, Fenglai Wang, Xiangfang Zeng
Abstract
. Furthermore, methionine enhanced the relative protein and mRNA expression of critical genes related to estrogen synthesis, ultimately increasing estrogen synthesis in primary ovarian granulosa cells. Taken together, our results suggested that methionine promoted follicular growth and estrogen synthesis in rats during the estrus cycle, which improved embryo implantation during early pregnancy. These findings provided a potential nutritional strategy to improve the reproductive performance of animals.
Topics & Concepts
Estrous cycleFollicular phaseEstrogenMethionineInternal medicineEndocrinologyBiologyAndrologyMedicineBiochemistryAmino acidBirth, Development, and HealthFolate and B Vitamins ResearchNutrition, Genetics, and Disease