Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain
Rocco Latorre, Paulina D. Ramírez-García, Alan Hégron, James L. Grace, Jeffri S. Retamal, Priyank A. Shenoy, Mai Tran, Luigi Aurelio, Bernard L. Flynn, Daniel P. Poole, Rafael Klein-Cloud, Dane D. Jensen, Thomas P. Davis, Brian L. Schmidt, John F. Quinn, Michael R. Whittaker, Nicholas A. Veldhuis, Nigel W. Bunnett
Topics & Concepts
EndosomeAprepitantAntagonistChronic painTachykinin receptor 1PharmacologyReceptor antagonistNociceptionNeuropathic painMaterials scienceMedicineSubstance PAnesthesiaReceptorNeuropeptideInternal medicineVomitingPsychiatryAntiemeticPain Mechanisms and TreatmentsNeuropeptides and Animal PhysiologyAdvancements in Transdermal Drug Delivery