Enhancing the thermostability of carboxypeptidase A by a multiple computer-aided rational design based on amino acids preferences at β-turns
Yue Ming, Haoxiang Zhang, Zitong Zhao, Zhenzhen Zhang, Honglei Wang, Zhihong Liang
Topics & Concepts
ThermostabilityCarboxypeptidaseHydrolysisRational designAmino acidChemistryMolecular dynamicsProtein engineeringDirected evolutionEnzymeBiochemistryMaterials scienceComputational chemistryNanotechnologyGeneMutantViral Infectious Diseases and Gene Expression in InsectsEnzyme Catalysis and ImmobilizationSteroid Chemistry and Biochemistry