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Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases

Scott C. Ritchie, Samuel A. Lambert, Matthew Arnold, Shu Mei Teo, Sol Lim, Petar Šćepanović, Jonathan Marten, Sohail Zahid, Mark Chaffin, Yingying Liu, Gad Abraham, Willem H. Ouwehand, David J. Roberts, Nicholas A. Watkins, Brian G. Drew, Anna C. Calkin, Emanuele Di Angelantonio, Nicole Soranzo, Stephen Burgess, Michael Chapman, Sekar Kathiresan, Amit V. Khera, John Danesh, Adam S. Butterworth, Michael Inouye

2021Nature Metabolism94 citationsDOIOpen Access PDF

Topics & Concepts

DiseaseQuantitative trait locusGenetic architectureAlleleType 2 diabetesBiologyProteomeBioinformaticsDiabetes mellitusGeneticsGenome-wide association studyMedicineGeneInternal medicineEndocrinologySingle-nucleotide polymorphismGenotypeGenetic Associations and EpidemiologyLiver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins
Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases | Litcius