Trimethyl Borate-Catalyzed, Solvent-Free Reductive Amination
P. Veeraraghavan Ramachandran, Shivani Choudhary, Aman Singh
Abstract
Solvent-free reductive amination of aldehydes and ketones with aliphatic and aromatic amines in high-to-excellent yields has been achieved with sub-stoichiometric trimethyl borate as promoter and ammonia borane as reductant.
Topics & Concepts
ChemistryReductive aminationBoraneAminationBoronCatalysisStoichiometrySolventOrganic chemistryAmmoniaBoranesAmmonia boraneDehydrogenationAsymmetric Hydrogenation and CatalysisChemical Synthesis and ReactionsChemical Synthesis and Analysis