A highly efficient transgene knock-in technology in clinically relevant cell types
Alexander G. Allen, Samia Khan, Carrie M. Margulies, Ramya Viswanathan, Swarali Surendra Lele, Laura Blaha, Sean Scott, Kaitlyn M. Izzo, Alexandra Gerew, Rithu Pattali, Nadire R. Cochran, Carl S. Holland, Amy H. Zhao, Stephen E. Sherman, Michael Jaskolka, Meng Wu, Aaron Wilson, Xiaoqi Sun, Dawn Ciulla, Deric Zhang, Jacqueline D. Nelson, Peisheng Zhang, Patrizia Mazzucato, Yan Huang, Georgia Giannoukos, Eugenio Marco, Michael Nehil, John A. Follit, Kai‐Hsin Chang, Mark S. Shearman, Christopher J. Wilson, John A. Zuris
Topics & Concepts
TransgeneGene knockinBiologyInduced pluripotent stem cellTranscription activator-like effector nucleaseGene targetingGene knockoutCRISPRExonGeneCell biologyGenome editingGeneticsEmbryonic stem cellMolecular biologyCRISPR and Genetic EngineeringCAR-T cell therapy researchVirus-based gene therapy research