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Exploring the Symbiotic Mechanism of a Virus-Mediated Endophytic Fungus in Its Host by Dual Unique Molecular Identifier–RNA Sequencing

Zheng Qu, Hongxiang Zhang, Qianqian Wang, Huizhang Zhao, Xiaofan Liu, Yànpíng Fù, Yang Lin, Jiǎtāo Xiè, Jiāsēn Chéng, Bo Li, Dàohóng Jiāng

2021mSystems18 citationsDOIOpen Access PDF

Abstract

Although endophytes are widespread in nature, the interactions between endophytes and their hosts are still not fully understood. Members of a unique class of endophytes, the virus-mediated endophytic fungi, are continuously being discovered and have received wide attention. In this study, we investigated the interaction between a mycovirus-mediated endophytic fungus and its host rapeseed by using dual-UMI RNA-seq. According to the dual-UMI RNA-seq results, an aerial view of symbiotic mechanism under balanced regulation was suggested. This research expands our understanding of the symbiotic mechanisms of virus-fungus-plant interactions and could establish a foundation for the further development of practical application with virus-mediated hypovirulent fungi.

Topics & Concepts

MycovirusBiologyHost (biology)FungusRNAMechanism (biology)Computational biologyEndophyteGeneGeneticsBotanyRNA polymerasePhilosophyEpistemologyPlant and Fungal Interactions ResearchPlant Virus Research StudiesPlant and fungal interactions
Exploring the Symbiotic Mechanism of a Virus-Mediated Endophytic Fungus in Its Host by Dual Unique Molecular Identifier–RNA Sequencing | Litcius