3D printing of artificial skin patches with bioactive and optically active polymer materials for anti-infection and augmenting wound repair
Hao Zhao, Jingwen Xu, Haitao Yuan, Endong Zhang, Nan Dai, Zhiqiang Gao, Yiming Huang, Fengting Lv, Libing Liu, Qi Gu, Shu Wang
Abstract
A printable ink composed of a photoactive cationic conjugated poly(phenylene vinylene) derivative (PPV) and gelatin/alginate/hyaluronic acid is developed for 3D printing artificial skin patches. This patch shows excellent photodynamic therapy-based anti-infection superiority and outstanding bioactivity to facilitate wound repair. This study contributes to design new conjugated polymer inks for manufacturing functional skin patches.
Topics & Concepts
GelatinHyaluronic acidArtificial skinCationic polymerizationPolymerMaterials scienceInkwellNatural polymersBiomedical engineeringNanotechnologyPolymer chemistryChemistryComposite materialOrganic chemistryMedicineAnatomy3D Printing in Biomedical ResearchWound Healing and TreatmentsAdditive Manufacturing and 3D Printing Technologies