Recyclable fluorous-tag assisted two-directional oligosaccharide synthesis enabled by interrupted Pummerer reaction mediated glycosylation
Lei Cai, Qi Chen, Jian Guo, Zhihua Liang, Dengxian Fu, Lingkui Meng, Jing Zeng, Qian Wan
Abstract
Recyclable fluorous-tag assisted IPRm glycosylation enabled efficient solution-phase synthesis and rapid fluorous purification, thus promoting sustainable two-directional oligosaccharide assembly.
Topics & Concepts
GlycosylationPummerer rearrangementChemistryOligosaccharideCombinatorial chemistryOrganic chemistryBiochemistryCatalysisAcetic anhydrideCarbohydrate Chemistry and SynthesisGlycosylation and Glycoproteins ResearchChemical Synthesis and Analysis