Anti-HLA serologic response to CD38-targeting desensitization therapy is challenged by peripheral memory B cells in highly sensitized kidney transplant candidates
Alba Torija, Matignon Marie, Flavio Vincenti, Franc Casanova‐Ferrer, Pilon Caroline, Anat R. Tambur, Laura Donadeu, Elena Crespo, Delphine Kervella, Maria Meneghini, Irina B. Torres, Florianne Hafkamp, Anna Martínez-Lacalle, Claudia Carrera, José Zúñiga, Amarpali Brar, Josep M. Cruzado, A. Osama Gaber, Helen Lee, Robert A. Montgomery, Mark D. Stegall, Maryvonnick Carmagnat, Cédric Usureau, Francesc Moreso, Philippe Grimbert, Oriol Bestard
Topics & Concepts
MedicineCD38DaratumumabImmunologySerologyDesensitization (medicine)Flow cytometryMemory B cellHuman leukocyte antigenBone marrowAntibodyAntigenB cellMonoclonal antibodyInternal medicineStem cellBiologyReceptorCD34GeneticsImmune Cell Function and InteractionRenal Transplantation Outcomes and TreatmentsT-cell and B-cell Immunology