Mn(<scp>iii</scp>)-mediated carbon-centered radicals generate an enhanced immunotherapeutic effect
Jiaxuan Li, Baifei Hu, Zelong Chen, Jiahui Li, Wenjuan Jin, Yi Wang, Yichen Wan, Yinghua Lv, Yuxin Pei, Hongtao Liu, Zhichao Pei
Abstract
to further strengthen ICD. This is the first report on Mn(iii)-mediated generation of carbon-centered radicals for successful anti-tumor immunotherapy using ICD, which provides a novel strategy for designing highly efficient cancer therapeutic nanovaccines.
Topics & Concepts
RadicalCancer researchTumor microenvironmentPhotodynamic therapyChemistryCell biologyTumor cellsMedicineBiologyBiochemistryOrganic chemistryNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisLuminescence and Fluorescent Materials