Gas plasma irradiation of breast cancers promotes immunogenicity, tumor reduction, and an abscopal effect in vivo
Hamed Mahdikia, Fariba Saadati, Eric Freund, Udo S. Gaipl, Keivan Majidzadeh‐A, Babak Shokri, Sander Bekeschus
Abstract
T-cells as well as dendritic cells in the tissues. In summary, we found gas plasma-irradiated murine breast cancers to induce toxicity and augmented immunogenicity, leading to reduced tumor growth at a site remote to the treatment area.
Topics & Concepts
ImmunogenicityImmunogenic cell deathCancer researchCD8Breast cancerTumor microenvironmentAbscopal effectCancerMedicineIn vivoImmunotherapyImmunologyImmune systemBiologyInternal medicineBiotechnologyPlasma Applications and DiagnosticsNanoplatforms for cancer theranosticsHeme Oxygenase-1 and Carbon Monoxide