Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis
Gai Gao, Zhishen Xie, Erwen Li, Yong Yuan, Yu Fu, Pan Wang, Xiaowei Zhang, Yonghui Qiao, Jiangyan Xu, Christian Hölscher, Hui Wang, Zhenqiang Zhang
Topics & Concepts
KEAP1GPX4Lipid peroxidationNonalcoholic fatty liver diseaseChemistryReactive oxygen speciesMalondialdehydeGlutathione peroxidaseHeme oxygenaseAntioxidantGlutathioneOxidative stressBiochemistryFatty liverHemeSuperoxide dismutaseInternal medicineEnzymeTranscription factorMedicineGeneDiseaseFerroptosis and cancer prognosisGenomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms