A chemically modified DNAzyme-based electrochemical sensor for binary and highly sensitive detection of reactive oxygen species

Abstract

and HClO) produced by cancer cells with high sensitivity across a broad linear range of 1 to 200 nM and a low detection limit in the sub-nanomolar range. The design strategies behind the developed ROS sensing system could also be exploited to create other biosensors with highly sensitive and binary detection to promote clinical research and revolutionize disease diagnostics.

Topics & Concepts