Discovery of potential active ingredients of Er-Zhi-Wan, a famous traditional Chinese formulation, in model rat serum for treating osteoporosis with kidney-yin deficiency by UPLC-Q/TOF-MS and molecular docking
Mengting Gao, Xin Xue, Xuemeng Zhang, Yueyue Chang, Qiulan Zhang, Xin Li, Yifei Wang, Zhang Li, Zhipeng Li, Haijuan Dong, Wei Wang, Weifeng Yao
Topics & Concepts
ChemistrySalidrosideHigh-performance liquid chromatographyChromatographyGlucuronidationPaeoniflorinActive ingredientPharmacologyBiochemistryIn vitroMicrosomeMedicineMedicinal Plants and Bioactive CompoundsDrug-Induced Hepatotoxicity and ProtectionParaoxonase enzyme and polymorphisms