Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses
Jacob C. Milligan, Carl W. Davis, Xiaoying Yu, Philipp A. Ilinykh, Kai Huang, Peter Halfmann, Robert W. Cross, Viktoriya Borisevich, Krystle N. Agans, Joan B. Geisbert, Chakravarthy Chennareddy, Arthur J. Goff, Ashley E. Piper, Sean Hui, Kelly Shaffer, Tierra K. Buck, Megan L. Heinrich, Luis M. Branco, Ian Crozier, Michael R. Holbrook, Jens H. Kuhn, Yoshihiro Kawaoka, Pamela J. Glass, Alexander Bukreyev, Thomas W. Geisbert, Gabriella Worwa, Rafi Ahmed, Erica Ollmann Saphire
Topics & Concepts
EpitopeBiologyVirologyMonoclonal antibodyAntibodyEbola virusEbolavirusParatopeGlycoproteinAntigenVirusMolecular biologyImmunologyViral Infections and Outbreaks ResearchSARS-CoV-2 and COVID-19 ResearchVirology and Viral Diseases