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Glycerol monolaurate attenuated immunological stress and intestinal mucosal injury by regulating the gut microbiota and activating AMPK/Nrf2 signaling pathway in lipopolysaccharide-challenged broilers

Linglian Kong, Zhenhua Wang, Chuanpi Xiao, Qidong Zhu, Zhigang Song

2022Animal nutrition54 citationsDOIOpen Access PDF

Abstract

were linked to attenuated inflammation and improved antioxidant capacity of challenged birds. In conclusion, dietary GML alleviated LPS-induced immunological stress and intestinal injury of broilers by suppressing inflammation and oxidative stress. Dietary GML regulated cecal microbiota and activated the AMPK/Nrf2 pathway in LPS-challenged broilers.

Topics & Concepts

LipopolysaccharideMalondialdehydeSuperoxide dismutaseBroilerAntioxidantImmunoglobulin ABiologyAMPKInternal medicineEndocrinologyBiochemistryChemistryProtein kinase AImmunologyImmunoglobulin GAntibodyFood scienceKinaseMedicineAnimal Nutrition and PhysiologyPharmacological Effects of Natural CompoundsGinseng Biological Effects and Applications
Glycerol monolaurate attenuated immunological stress and intestinal mucosal injury by regulating the gut microbiota and activating AMPK/Nrf2 signaling pathway in lipopolysaccharide-challenged broilers | Litcius