Degrading mutant IDH1 employing a PROTAC-based approach impairs STAT3 activation
Hashnu Dutta, Nishant Jain
Topics & Concepts
MutantChemistryComputational biologyCell biologyBiochemistryBiologyGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments