Ferroptosis and the cGAS–STING pathway into precision nano-immuno-theranostics: A mechanistic paradigm for reversing drug resistance in hepatocellular carcinoma
Alaa Elmetwalli
Topics & Concepts
Precision medicineTumor microenvironmentCancer researchHepatocellular carcinomaMedicineDrug resistanceTranslational medicineCancerLimitingImmunotherapyProgrammed cell deathAutophagyCancer cellMechanism (biology)Computational biologyTranslation (biology)Tumor progressionImmune checkpointCombination therapySignal transductionTargeted therapyDrug discoveryDrugBioinformaticsComputer scienceSystems biologyCancer immunotherapyClinical PracticeDrug developmentAcquired resistanceLiver cancerSonodynamic therapyRegulatorFerroptosis and cancer prognosisinterferon and immune responsesNanoplatforms for cancer theranostics