Design, synthesis, biological evaluation, and docking study of new triazole-phenylacetamide derivatives as α-glucosidase inhibitors
Shuang Luo, Wei Yang, Yong Huang, Zhiyun Peng, Guangcheng Wang
Topics & Concepts
ChemistryAcarboseIC50Docking (animal)Circular dichroismCytotoxicityPostprandialActive siteEnzymeStereochemistryLead compoundIn vitroBiochemistryTriazoleCombinatorial chemistryOrganic chemistryNursingInsulinMedicineEndocrinologyNatural Antidiabetic Agents StudiesSynthesis and biological activityComputational Drug Discovery Methods