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Drugging the Undruggable and beyond: Emerging precision oncology approaches to target acquired resistance to KRAS G12C and KRAS G12D inhibitors

Ramesh R. Kale, Charudatt Samant, Krishnadas Nandakumar, K. Sreedhara Ranganath Pai, Mandar Bhonde

2025Biochemical and Biophysical Research Communications8 citationsDOI

Topics & Concepts

KRASMedicinePrecision oncologyCancer researchPharmacologyOncologyInternal medicineCancerColorectal cancerProtein Kinase Regulation and GTPase SignalingMelanoma and MAPK PathwaysPI3K/AKT/mTOR signaling in cancer
Drugging the Undruggable and beyond: Emerging precision oncology approaches to target acquired resistance to KRAS G12C and KRAS G12D inhibitors | Litcius