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A novel MRGPRX2-targeting antagonistic DNA aptamer inhibits histamine release and prevents mast cell-mediated anaphylaxis

Yasuyuki Suzuki, Shuang Liu, Tomio Ogasawara, Tatsuya Sawasaki, Yasushi Takasaki, Toshihiro Yorozuya, Masaki Mogi

2020European Journal of Pharmacology43 citationsDOI

Topics & Concepts

HistamineMast cellAnaphylaxisChemistryHistamine H4 receptorPharmacologyDNACell biologyImmunologyBiologyHistamine H2 receptorAllergyBiochemistryReceptorAntagonistMast cells and histamineFood Allergy and Anaphylaxis ResearchPolyamine Metabolism and Applications
A novel MRGPRX2-targeting antagonistic DNA aptamer inhibits histamine release and prevents mast cell-mediated anaphylaxis | Litcius