Beyond organic solvents: synthesis of a 5-HT<sub>4</sub> receptor agonist in water
J. Daniel Bailey, Edward Helbling, Amey Mankar, Matthew Stirling, Fred A. Hicks, David K. Leahy
Abstract
A manufacturing process conducted almost entirely in water has been developed to produce <bold>TAK-954</bold>, an investigational 5-HT<sub>4</sub> receptor agonist.
Topics & Concepts
AgonistChemistryReceptorOrganic chemistryCombinatorial chemistryBiochemistryChemistry and Chemical EngineeringInnovative Microfluidic and Catalytic Techniques InnovationIonic liquids properties and applications